Home
HelpTest Code MYGLS Myoglobin, Serum
Reporting Name
Myoglobin, SUseful For
Assessing muscle damage from any cause
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Specimen Minimum Volume
0.6 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 365 days | ||
| Ambient | 7 days |
Reference Values
Males: 0 to 72 mcg/L
Females: 0 to 58 mcg/L
CPT Code Information
83874
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MYGLS | Myoglobin, S | 2639-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| MYGLS | Myoglobin, S | 2639-3 |
Clinical Information
Myoglobin is a heme protein found in smooth and skeletal muscles. Serum myoglobin reflects a balance between intravascular release of myoglobin from muscle and renal clearance.
Previously serum myoglobin had been advocated as a sensitive marker for early acute myocardial injury (eg, acute myocardial infarction: AMI). However, more recent studies indicate that newer markers (eg, troponin) provide superior diagnostic utility in detecting early myocardial injury.
Elevation of serum myoglobin may occur as a result of muscle trauma, resuscitation, myopathies, AMI, shock, strenuous body activity, or decreased elimination during renal insufficiency. Extreme elevations occur in rhabdomyolysis. Creatine kinase is released from muscle and used more commonly for this purpose.
Interpretation
Elevated myoglobin levels are seen in conditions of acute muscle injury.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Method Name
Electrochemiluminescent Immunoassay (ECLIA)