Test Code MONO Monospot
Specimen Information
Obtain specimen using standard phlebotomy techniques.
No special patient preparation is necessary.
Container | Specimen | Temperature | Collect Vol | Submit Vol | Min Vol | Stability |
SST | Serum | Refrigerate | 4.0 mL | 1.0 mL | 0.6 mL | 3 days |
Purple Top (EDTA) | Plasma | Refrigerate | 4.0 mL | 1.0 mL | 0.6 mL | 3 days |
Reject Due To:
- Marked Hemolysis
- Specimen unlabeled or mislabeled
Instrumentation / Method
Color MONO Qualitative Latex Test
Test Schedule / Analytical Time / Test Priority
Daily / Same Day / Available STAT
Reference Range
Nonreactive
False negative results have been reported. Some of these may represent cases of infectious mononucleosis (IM) which persistently remain sero-negative for the IM heterophil antibody. However, some false negative results have been shown to be due to a delayed IM heterophil antibody response.
Patients with exceptionally high levels of the serum sickness heterophil antibody may test falsely positive for the IM heterophil. These patients are generally found in counrties where horse serum is used prophylactically.
The IM heterophil has been associated with several diseases other than IM. These include leukemia, Burkitt's lymphoma, pancreatic carcinoma, viral hepatitis, CMV infections, and others.
CPT / LOINC / Order Code
Meditech | Medent | LOINC | CPT |
MONO | MONO | 31418-7 | 86308 |