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HelpTest Code FPOLO Poliovirus (Types 1, 3) Antibodies, Neutralization
Specimen Required
Specimen Type: Serum
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge and aliquot 1 mL of serum into a plastic vial.
2. Ship refrigerated.
Secondary ID
75165Method Name
Culture/Neutralization
Reporting Name
Poliovirus (Types 1, 3) Ab, NeutSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 5 days |
Clinical Information
This sensitive procedure is recommended for vaccine response testing and type-specific serodiagnosis of recent poliovirus infection. It can also serve as an aid for diagnosing immune deficiency disorders.
Reference Values
Polio 1 Titer: <1:8
Polio 3 Titer: <1:8
CPT Code Information
86382 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FPOLO | Poliovirus (Types 1, 3) Ab, Neut | 68320-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z4806 | Polio 1 Titer | 22446-9 |
| Z4807 | Polio 3 Titer | 22450-1 |
Reject Due To
All specimens will be evaluated at the performing laboratory for test suitability.Interpretation
The presence of neutralizing serum antibodies (titers 1:8 up to >1:128) against polioviruses implies lifelong immunity. Some persons without detectable titers (<1:8) may also be immune as demonstrated by elicitation of a secondary-type serum antibody response upon rechallenge with live polio vaccine.