Test Code ETGSR Ethyl Glucuronide Screen with Reflex, Random, Urine
Specimen Required
Only orderable as part of profile. For more information see CSMEU / Controlled Substance Monitoring Enhanced Profile with Reflex, 21 Drug Classes, High Resolution Mass Spectrometry and Immunoassay Screen, Random, Urine.
Container/Tube: Plastic, 60-mL urine bottle
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Secondary ID
616033Useful For
Screening for drug abuse involving alcohol
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
ETGC | Ethyl Glucuronide Confirmation, U | Yes | No |
Testing Algorithm
Testing begins with a screening assay. If the screen is positive, then the liquid chromatography-tandem mass spectrometry confirmation with quantification will be performed at an additional charge.
Method Name
Only orderable as part of profile. For more information see CSMEU / Controlled Substance Monitoring Enhanced Profile with Reflex, 21 Drug Classes, High Resolution Mass Spectrometry and Immunoassay Screen, Random, Urine.
Immunoassay
Reporting Name
Ethyl Glucuronide Scrn w/Reflex, USpecimen Type
UrineSpecimen Minimum Volume
2.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 28 days | |
Frozen | 28 days | ||
Ambient | 72 hours |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Clinical Information
This procedure uses immunoassay reagents designed to produce a negative result when no drugs are present in a natural (ie, unadulterated) urine specimen; the assay is designed to have a high true-negative rate. Like all immunoassays, it can have a false-positive rate due to cross-reactivity with natural chemicals and drugs other than those they were designed to detect. The immunoassay also has a false-negative rate to the antibody's ability to cross-react with different drugs in the class being screened.
Ethyl glucuronide is a direct metabolite of ethanol formed by enzymatic conjugation of ethanol with glucuronic acid. Alcohol in urine is normally detected for only a few hours, whereas ethyl glucuronide can be detected in the urine for 1 to 3 days.
Reference Values
Only orderable as part of profile. For more information see CSMEU / Controlled Substance Monitoring Enhanced Profile with Reflex, 21 Drug Classes, High Resolution Mass Spectrometry and Immunoassay Screen, Random, Urine.
Negative
Screening cutoff concentration:
Ethyl Glucuronide: 500 ng/mL
Interpretation
This assay only provides a preliminary analytical test result. A more specific alternative method (ie, liquid chromatography-tandem mass spectrometry) must be used to obtain a confirmed analytical result. A positive result using the ethyl glucuronide screen indicates only the potential presence of ethyl glucuronide and does not necessarily correlate with the extent of physiological and psychological effects.
CPT Code Information
80307
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ETGSR | Ethyl Glucuronide Scrn w/Reflex, U | 58375-7 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
616033 | Ethyl Glucuronide Screen, U | 58375-7 |