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Test Code ETGC Ethyl Glucuronide Confirmation, Random, Urine


Ordering Guidance


For situations where chain of custody is required, a Chain of Custody Kit (T282) is available. For chain-of-custody testing, order ETGX / Ethyl Glucuronide Confirmation, Chain of Custody, Random, Urine.

 

Additional drug panels and specific requests are available: call 800-533-1710.



Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Random, Urine.

Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Aliquot tube, 5 mL

Specimen Volume: 1 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting less than 1 mL will compromise our ability to perform all necessary testing.


Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.

Secondary ID

63421

Useful For

Monitoring abstinence in clinical and justice system settings

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Ethyl Glucuronide Confirmation, U

Specimen Type

Urine

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Clinical Information

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are minor metabolites of ethanol that are detectable in body fluids following alcohol consumption and, less commonly, following extraneous exposure. EtG and EtS can be detected up to 5 days in urine using a cutoff of 500 ng/mL.(1)

Reference Values

Negative

Interpretation

A positive interpretation will be given if either the ethyl glucuronide (EtG) result is greater than or equal to 250 ng/mL or the ethyl sulfate (EtS) is greater than or equal to 100 ng/mL.

 

A "high" positive (ie, >1000 ng/mL) may indicate:

-Heavy drinking on the same day or previously (ie, previous day or 2).

-Light drinking the same day

 

A "low" positive (ie, 500-1000 ng/mL) may indicate:

-Previous heavy drinking (ie, previous 1-3 days)

-Recent light drinking (ie, past 24 hours)

-Recent intense "extraneous" exposure (ie, within 24 hours or less)

 

A "very low" positive (ie, 100-500 ng/mL) may indicate:

-Previous heavy drinking (ie, 1-3 days)

-Previous light drinking (ie, 12-36 hours)

-Recent "extraneous" exposure(2)

CPT Code Information

80321; G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ETGC Ethyl Glucuronide Confirmation, U 93705-2

 

Result ID Test Result Name Result LOINC Value
63421 Ethyl Glucuronide 58378-1
36848 Ethyl Sulfate 58425-0
36849 Ethyl Gluc/Sulfate Interpretation 69050-3