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Test Code CDB Cadmium, Blood

Reporting Name

Cadmium, B

Useful For

Detecting exposure to cadmium, a toxic heavy metal

Specimen Type

Whole blood


Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Metal Free B-D Tube (EDTA), 6 mL (T183)

Container/Tube: Royal blue top (EDTA) plastic trace element blood collection tube

Specimen Volume: Full tube

Collection Instructions:

1. See Metals Analysis Specimen Collection and Transport  for complete instructions.

2. Send whole blood specimen in original collection tube. Do not aliquot.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

<5.0 ng/mL

Reference values apply to all ages.

CPT Code Information

82300

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CDB Cadmium, B 5609-3

 

Result ID Test Result Name Result LOINC Value
8682 Cadmium, B 5609-3

Clinical Information

The toxicity of cadmium resembles the other heavy metals (arsenic, mercury, and lead) in that it attacks the kidney; kidney dysfunction with proteinuria with slow onset (over a period of years) is the typical presentation.

 

Breathing the fumes of cadmium vapors leads to nasal epithelial deterioration and pulmonary congestion resembling chronic emphysema.

 

The most common source of chronic exposure comes from spray painting organic-based paints without a protective breathing apparatus; auto repair mechanics represent a susceptible group for cadmium toxicity. In addition, another common source of cadmium exposure is tobacco smoke.

Interpretation

Normal blood cadmium is less than 5.0 ng/mL, with most results in the range of 0.5 to 2.0 ng/mL.

 

Acute toxicity will be observed when the blood level exceeds 50 ng/mL.

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)

Secondary ID

8682