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HelpTest Code BNP-NTPRO NT-proBNP
Specimen Information
Obtain specimen using standard phlebotomy techniuques.
No special patient preparation is necessary.
| Container | Specimen | Temperature | Collect Vol | Submit Vol | Min Vol | Stability |
| SST | Serum | Refrigerate | 4 mL | 1.0 mL | 0.75 mL | 3 days |
| Lithium Heparin | Plasma | Refrigerate | 4 mL | 1.0 mL | 0.75 mL | 3 days |
Reject Due To:
- Moderate or Marked Hemolysis
- Specimen unlabeled or mislabeled
Instrumentation / Method
Ortho Vitros XT 7600 / Immunoturbidometric
Reference Range
| NT-proBNPII Result (pg/mL) | Age Group (years) | Interpretation |
| <300 | All | Negative |
| ≥300 to <450 | 22 - <55 | Indeterminate |
| ≥300 to <900 | 50 - <75 | |
| ≥300 to <1800 | ≥75 | |
| ≥450 | 22 - <55 |
Positive |
| ≥900 | 50 - <75 | |
| ≥1800 | ≥75 |
Reference ranges apply to patients presenting to the ED setting with acute or worsening dyspnea. For patients in an outpatient setting the test has a very low positive predictive value.In an outpatient setting consider any result <125 pg/mL as negative. For results ≥125 pg/mL, correlation with at least one sign, symptom, or risk factor can be used to identify patients that will need further cardiac investigation.
CPT / LOINC / Order Code
| Meditech | Medent | LOINC | CPT |
| BNP-NTPROS | BNP-NTPROS | 33762-6 | 83880 |
Test Schedule / Analytic Time / Test Priority
Daily / Same Day / Available STAT